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For the Database and parameters I suggest to read the docs and search the forum posts to learn more about it. Do not blindly apply numbers.
Straight from the documentation:
https://docs.zammad.org/en/latest/prerequisites/hardware.html#performance-tuning
https://docs.zammad.org/en/latest/appendix/configure-env-vars.html#performance-tuning
Some interesting threads:
Sorry for not giving straight answers, but it highly depends on your setup.
e.g. Elasticsearch will also eat up resources while indexing, etc…