I’ve seen others mention opening and closing tickets automatically from PRTG but I haven’t found a detailed description of how exactly they are achieving this.
I do not use notification summarization. Perhabs you will receive a lot of emails, but that forces you to optimze your prtg f.e. by using dependencies.
I also created a own notification rule in prtg that sends notifications after 120 sec. So I hope that short issues do not create a ticket everytime. But that really depends on your support and ticket concept.