You did just update Zammad or possibly even your system?
Please ensure that your mail server does support the ciphers the operation system of your Zammad installation supports.
So I suppose you did upgrade your OS.
In that case you’ll have to ensure that your mail server does support the Ciphers. This is technically not a Zammad issue but an issue with your mail server and OS.
When upgrading distributions (and sometimes openssl versions) sometimes ciphers are dropped for security reasons.